Can Fluorine-18 Fluoroestradiol Positron Emission Tomography–Computed Tomography Demonstrate the Heterogeneity of Breast Cancer In Vivo?

• Published in: Clinical breast cancer Vol. 13; no. 5; pp. 359 - 363
• Main Authors: Yang, Zhongyi, Sun, Yifei, Zhang, Yongping, Xue, Jing, Wang, Mingwei, Shi, Wei, Zhu, Beiling, Hu, Silong, Yao, Zhifeng, Pan, Herong, Zhang, Yingjian
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2013
• Subjects: Adult; Aged; Breast cancer; Breast Neoplasms - diagnostic imaging; Breast Neoplasms - genetics; Breast Neoplasms - pathology; Estradiol - analogs & derivatives; Estrogen receptor; Female; Fluorine Radioisotopes; Fluorine-18 fluorodeoxyglucose positron emission tomography; fluorine-18 fluoroestradiol positron emission tomography; Genetic Heterogeneity; Hematology, Oncology and Palliative Medicine; Heterogeneity; Humans; Middle Aged; Multimodal Imaging; Neoplasm Metastasis; Obstetrics and Gynecology; Positron-Emission Tomography - methods; Receptors, Estrogen - genetics; Receptors, Estrogen - metabolism; Retrospective Studies; Tomography, X-Ray Computed - methods; Estrogen receptor; fluorine-18 fluoroestradiol positron emission tomography; Heterogeneity; Breast cancer; Fluorine-18 fluorodeoxyglucose positron emission tomography
• ISSN: 1526-8209; 1938-0666
• DOI: 10.1016/j.clbc.2013.02.012

Micro-Abstract Clarifying the estrogen receptor extent is important for treatment. We investigated the heterogeneity of estrogen receptor expression in 32 breast cancer patients by using fluorine-18 fluoroestradiol positron emission tomography–computed tomography, which demonstrated a conspicuous number of patients with the heterogeneity.