Liver Transplantation-Associated Lung Cancer: Comparison of Clinical Parameters and Outcomes

• Published in: Clinical lung cancer Vol. 16; no. 5; pp. e75 - e81
• Main Authors: Kocher, Florian, Finkenstedt, Armin, Fiegl, Michael, Graziadei, Ivo, Gamerith, Gabriele, Oberaigner, Wilhelm, Vogel, Wolfgang, Hilbe, Wolfgang
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2015
• Subjects: Aged; Clinical characteristics; Female; Follow-Up Studies; Hematology, Oncology and Palliative Medicine; Humans; Incidence; Liver transplantation; Liver Transplantation - adverse effects; Liver Transplantation - methods; Lung cancer; Lung Neoplasms - epidemiology; Lung Neoplasms - etiology; Lung Neoplasms - pathology; Male; Mass Screening - methods; Middle Aged; Prognosis; Pulmonary/Respiratory; Registries; Retrospective Studies; Smoking - adverse effects; Smoking - epidemiology; Survival; Survival Rate; Clinical characteristics; Survival; Lung cancer; Incidence; Liver transplantation
• ISSN: 1525-7304; 1938-0690
• DOI: 10.1016/j.cllc.2015.02.003

Micro-Abstract We performed a retrospective comparison of patients with postliver transplantation lung cancer (PLTLC), patients with transplant-naive lung cancer, and patients with liver transplantation. The standardized incidence ratio for lung cancer in liver recipients was 4.4 in the women and 2.6 in the men. Post-transplant survival was reduced in the PLTLC group; the overall survival (OS) after the diagnosis of lung cancer was similar. OS after lung cancer does not seem to be reduced by liver transplantation. Considering the increased incidence, routine screening should be considered for liver transplantation patients with a history of smoking.