Cardiovascular Disease Risk in Patients with Rheumatic Diseases

Evidence suggests the greater than 1.5 increased risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA) is related to an accelerated burden of subclinical atherosclerosis that develops before the diagnosis of RA. Dyslipidemia in RA is better quantified by lipoproteins and apolipoproteins...

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Bibliographic Details
Published inClinics in geriatric medicine Vol. 33; no. 1; p. 105
Main Authors Mackey, Rachel H, Kuller, Lewis H, Moreland, Larry W
Format Journal Article
LanguageEnglish
Published United States 01.02.2017
Subjects
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Global Health
Humans
Morbidity
Rheumatic Diseases - complications
Rheumatic Diseases - epidemiology
Risk Factors
Survival Rate
Lipids
Lipoproteins
Myocardial fibrosis
Cardiovascular
Rheumatoid arthritis
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Summary:Evidence suggests the greater than 1.5 increased risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA) is related to an accelerated burden of subclinical atherosclerosis that develops before the diagnosis of RA. Dyslipidemia in RA is better quantified by lipoproteins and apolipoproteins than cholesterol levels. Current risk factors likely underestimate CVD risk partly by underestimating prior risk factor levels. To reduce CVD risk in RA, control disease activity and aggressively treat CVD risk factors. Some of the two-fold higher risk of heart failure and total mortality in RA may be due to myocardial disease caused by inflammation.
ISSN:1879-8853
DOI:10.1016/j.cger.2016.08.008