Update on Crystal-Induced Arthritides

The prevalence of gout increases with age. Once serum concentration of urate exceeds the saturation/solubility point, it deposits in and around the joints. Clinical presentation in the elderly often has "atypical" features and is challenging to diagnose. Treatment depends on the stage of t...

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Bibliographic Details
Published inClinics in geriatric medicine Vol. 33; no. 1; p. 135
Main Authors El-Zawawy, Hossam, Mandell, Brian F
Format Journal Article
LanguageEnglish
Published United States 01.02.2017
Subjects
Aged
Global Health
Gout - blood
Gout - diagnosis
Gout - epidemiology
Humans
Morbidity
Prevalence
Uric Acid - blood
Comorbidities
Treat to target
Gout
Geriatrics
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Summary:The prevalence of gout increases with age. Once serum concentration of urate exceeds the saturation/solubility point, it deposits in and around the joints. Clinical presentation in the elderly often has "atypical" features and is challenging to diagnose. Treatment depends on the stage of the disease and the patient's health status and comorbidities. Elderly patients often have several confounding issues; thus, treatment decisions can be complicated and therapeutic options limited. To prevent the recurrence of gout attacks, serum concentration of urate should be maintained well below the saturation threshold of 6.8 mg/dL, leading to dissolution of urate deposits and prevent recurrence.
ISSN:1879-8853
DOI:10.1016/j.cger.2016.08.010