Novel coronavirus in a 15-day-old neonate with clinical signs of sepsis, a case report

• Published in: Infectious diseases (London, England) Vol. 52; no. 6; pp. 427 - 429
• Main Authors: Kamali Aghdam, Mojtaba, Jafari, Nahid, Eftekhari, Kambiz
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 02.06.2020
• Subjects: Anti-Bacterial Agents - therapeutic use; Antiviral Agents - therapeutic use; Betacoronavirus; Case Report; Clinical Laboratory Techniques; Coronavirus Infections - diagnosis; Coronavirus Infections - drug therapy; Humans; Infant, Newborn; Male; Pandemics; Pneumonia, Viral - diagnosis; Pneumonia, Viral - drug therapy; Reverse Transcriptase Polymerase Chain Reaction; Sepsis - virology; COVID-19; Neonates; novel coronavirus; sepsis
• ISSN: 2374-4235; 2374-4243
• DOI: 10.1080/23744235.2020.1747634

Novel coronavirus or coronavirus disease (COVID-19) can affect all age groups. The clinical course of the disease in children and infants is milder than in adults. It should be noted that, although typical symptoms may be present in children, non-specific symptoms could be noted in the neonate. The disease is rare in the neonate, so, its suspicion in this group can help to make a quick diagnose. A 15-day-old neonate was admitted with fever, lethargy, cutaneous mottling, and respiratory distress without cough. His mother had symptoms of Novel coronavirus. So Reverse-Transcription Polymerase Chain Reaction (RT-PCR) assay was done for the neonate and showed to be positive. The newborn was isolated and subjected to supportive care. Antibiotic and antiviral treatment was initiated. Eventually, the baby was discharged in good general condition. When a newborn presents with non-specific symptoms of infection with an added history of COVID-19 in his/her parents, it indicates the need for PCR testing for Novel coronavirus.