Clinical features of 10 cases of eyelid sporotrichosis in Jilin Province (Northeast China)

• Published in: Canadian journal of ophthalmology Vol. 51; no. 4; pp. 297 - 301
• Main Authors: Fan, Bin, PhD, MD, Wang, Jin-Feng, PhD, MD, Zheng, Bin, MD, Qi, Xin-Zhu, MD, Song, Jing-Yao, MD, Li, Guang-Yu, PhD, MD
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.08.2016
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents - therapeutic use; Child; Child, Preschool; China; Eye Infections, Fungal - diagnosis; Eye Infections, Fungal - drug therapy; Eye Infections, Fungal - microbiology; Eyelid Diseases - diagnosis; Eyelid Diseases - drug therapy; Eyelid Diseases - microbiology; Female; Humans; Internal Medicine; Male; Middle Aged; Naphthalenes - therapeutic use; Ophthalmology; Retrospective Studies; Sporothrix - isolation & purification; Sporotrichosis - diagnosis; Sporotrichosis - drug therapy; Sporotrichosis - microbiology
• ISSN: 0008-4182; 1715-3360
• DOI: 10.1016/j.jcjo.2016.02.018

Abstract Objective Sporotrichosis is a common subcutaneous mycosis caused by an infection with dimorphic fungus Sporothrix schenckii . We present a series of patients with eyelid sporotrichosis and study the clinical and histopathological presentation, microbiology, treatment options, and outcome. Methods A retrospective case-series study of patients with a clinical diagnosis of eyelid sporotrichosis. Records were examined to obtain information regarding patient demographics, presenting symptoms and signs, histopathological examination, microbiology, management, and outcomes. Results Ten patients (4 men, 6 women; mean age 46.5 years, range 3–81 years) were included. Based on their clinical manifestations, eyelid sporotrichosis was classified into 3 major forms: ( i ) fixed cutaneous (6/10 cases), ( ii ) lymphocutaneous (3/10 cases), and ( iii ) eyelid abscess (1/10 cases). All the cases were treated with a terbinafine 12-week regimen. Nodules, papules, and abscesses regressed after treatment. No recurrence was discovered after a 12-week follow-up. Conclusions Eyelid sporotrichosis has typical features of clinical manifestations. Histopathological examination and tissue culture are helpful for diagnosis. Confirmed cases normally require long-term systematic treatment with antifungal agents, but surgical removal is normally unnecessary.