Leukocyte Esterase Reagent Strips for the Rapid Diagnosis of Periprosthetic Joint Infection
Abstract A total of 223 consecutive total hip or total knee arthroplasties were evaluated for periprosthetic joint infection (PJI) using leukocyte esterase reagent (LER) strips. Fifty-two LER strips were read as positive (23.3%), 106 were read as negative (47.5%), and 65 strips (29.2%) were unable t...
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Published in | The Journal of arthroplasty Vol. 27; no. 8; pp. 8 - 11 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
01.09.2012
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Subjects | |
Online Access | Get full text |
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Summary: | Abstract A total of 223 consecutive total hip or total knee arthroplasties were evaluated for periprosthetic joint infection (PJI) using leukocyte esterase reagent (LER) strips. Fifty-two LER strips were read as positive (23.3%), 106 were read as negative (47.5%), and 65 strips (29.2%) were unable to be read secondary to debris or blood in the aspiration. Using a synovial fluid white blood cell count of greater than 3000 white blood cell per microliter as an indicator of PJI, the sensitivity and specificity were 92.9% and 88.8%, respectively. When using positive cultures for diagnosis of PJI, sensitivity and specificity were 93.3% and 77.0% and 100% and 86.8% for the cases where a reoperation was performed and a combination of factors were used to define PJI. Leukocyte esterase reagent strips represent a rapid, inexpensive, and sensitive tool for the diagnosis of PJI. Their utility is limited, however, by blood or debris in the synovial fluid rendering them unreadable in one-third of cases. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0883-5403 1532-8406 |
DOI: | 10.1016/j.arth.2012.03.037 |