T2 mapping with background gradient correction using different excitation pulse shapes

Background gradients induced by magnetic susceptibility variations near air-filled cavities in the brain cause signal-intensity loss in gradient-echo images and shorten T2* considerably. With a correction method in which the exponential decay is restored with section-profile-dependent correction fac...

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Bibliographic Details
Published inAmerican journal of neuroradiology : AJNR Vol. 34; no. 6; pp. E65 - E68
Main Authors Hirsch, N M, Preibisch, C
Format Journal Article
LanguageEnglish
Published United States American Society of Neuroradiology 01.06.2013
Subjects
Echo-Planar Imaging - methods
Humans
Image Enhancement - methods
Image Interpretation, Computer-Assisted - methods
Models, Theoretical
Parkinson Disease - pathology
Technical Notes
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Summary:Background gradients induced by magnetic susceptibility variations near air-filled cavities in the brain cause signal-intensity loss in gradient-echo images and shorten T2* considerably. With a correction method in which the exponential decay is restored with section-profile-dependent correction factors, parts of the signal intensity can be recovered. While uncorrected T2* values drop by 20% at a gradient strength of 75 μT/m, with correction and exponential excitation pulses, this boundary is pushed to 220 μT/m.
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ISSN:0195-6108
1936-959X
DOI:10.3174/ajnr.A3021