Systems Approaches to Cancer Biology

Cancer systems biology aims to understand cancer as an integrated system of genes, proteins, networks, and interactions rather than an entity of isolated molecular and cellular components. The inaugural Systems Approaches to Cancer Biology Conference, cosponsored by the Association of Early Career C...

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Published inCancer research (Chicago, Ill.) Vol. 76; no. 23; pp. 6774 - 6777
Main Authors Archer, Tenley C, Fertig, Elana J, Gosline, Sara J C, Hafner, Marc, Hughes, Shannon K, Joughin, Brian A, Meyer, Aaron S, Piccolo, Stephen R, Shajahan-Haq, Ayesha N
Format Journal Article
LanguageEnglish
Published United States 01.12.2016
Subjects
Humans
Neoplasms
Systems Biology - methods
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Summary:Cancer systems biology aims to understand cancer as an integrated system of genes, proteins, networks, and interactions rather than an entity of isolated molecular and cellular components. The inaugural Systems Approaches to Cancer Biology Conference, cosponsored by the Association of Early Career Cancer Systems Biologists and the National Cancer Institute of the NIH, focused on the interdisciplinary field of cancer systems biology and the challenging cancer questions that are best addressed through the combination of experimental and computational analyses. Attendees found that elucidating the many molecular features of cancer inevitably reveals new forms of complexity and concluded that ensuring the reproducibility and impact of cancer systems biology studies will require widespread method and data sharing and, ultimately, the translation of important findings to the clinic. Cancer Res; 76(23); 6774-7. ©2016 AACR.
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Authors arranged alphabetically and contributed equally.
ISSN:0008-5472
1538-7445
DOI:10.1158/0008-5472.CAN-16-1580