Surgical outcome for Moyamoya disease - clinical and perfusion computed tomography correlation

• Published in: World neurosurgery Vol. 98; pp. 81 - 88
• Main Authors: Cheung, Alvin Ho-Kwan, MBBS(HK), Lam, Angus Ka-Cheong, MBBS(HK), FHKAM(Radiology), Ho, Wai-Shing Wilson, MBBS(HK), FRCSEd, Tsang, Chun-Pong, MBBS(HK), FCSHK, Tsang, Anderson Chun-On, MBBS(HK), Lee, Raymond, MBBS(HK, FHKAM (Radiology), Lui, Wai-Man, MBBS(HK), FRCSEd, Leung, Gilberto Ka-Kit, MBBS(London), MS, FRCSEd
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2017
• Subjects: Adult; Cerebral Angiography; Cerebral Revascularization - methods; Cerebrovascular Circulation - physiology; Child; Cohort Studies; Coronary Artery Bypass - methods; Extracranial-intracranial bypass; Female; Humans; Male; Middle Cerebral Artery - diagnostic imaging; Middle Cerebral Artery - surgery; Moyamoya disease; Moyamoya Disease - diagnostic imaging; Moyamoya Disease - surgery; Neurosurgery; Perfusion; Perfusion computed tomography; Pia Mater - blood supply; Pia Mater - diagnostic imaging; Pia Mater - surgery; Statistics, Nonparametric; Tomography, X-Ray Computed; Treatment Outcome; Perfusion computed tomography; Extracranial-intracranial bypass; Moyamoya disease; CT; STA; EC-IC; PCCBF; MRI; CBF; MCA; CVRC; CTP
• ISSN: 1878-8750; 1878-8769
• DOI: 10.1016/j.wneu.2016.10.117

Highlights • Extensive data over 14 years was analysed and correlated with perfusion CT. • Bypass improved cerebrovascular reserve capacity more than synangiosis in adults. • Bypass may pose a greater risk of complication or deterioration. • Contralateral non-intervened hemisphere also benefited from surgery. • Perfusion CT after surgery were studied by time-points and subgroup analyses. • Clinical outcomes were analyzed by subgroups defined by presenting symptoms.