Imaging Registries and Single-Center Series

Abstract Randomized controlled trials are often regarded as the pinnacle of research designs, valued for their rigor and internal validity. However, their high costs and selected patient populations limit their applicability, and complementary study designs are needed to guide evidence. In the realm...

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Bibliographic Details
Published inJACC. Cardiovascular imaging Vol. 10; no. 3; pp. 276 - 285
Main Authors Hachamovitch, Rory, MD, MSc, Peña, Jessica M., MD, MPH, Xie, Joe, MD, MSCR, Shaw, Leslee J., PhD, Min, James K., MD
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.03.2017
Subjects
Cardiac Imaging Techniques - economics
Cardiac Imaging Techniques - trends
Cardiovascular
Cardiovascular Diseases - diagnostic imaging
Cardiovascular Diseases - economics
Cardiovascular Diseases - therapy
cardiovascular imaging
Cost-Benefit Analysis
Forecasting
Health Care Costs
Humans
Multicenter Studies as Topic
Observational Studies as Topic
Practice Patterns, Physicians
Predictive Value of Tests
Prognosis
Randomized Controlled Trials as Topic
Registries
Reproducibility of Results
Research Design
single-center series
coronary artery disease
computed tomography
RCT
myocardial perfusion imaging
CAD
MPI
CMR
randomized clinical trial
registries
cardiovascular
single-center series
EHR
SPECT
CT
CTA
CV
computed tomographic angiography
cardiovascular imaging
positron emission tomography
cardiac magnetic resonance
electronic health record
PET
single-photon emission computed tomography
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Summary:Abstract Randomized controlled trials are often regarded as the pinnacle of research designs, valued for their rigor and internal validity. However, their high costs and selected patient populations limit their applicability, and complementary study designs are needed to guide evidence. In the realm of cardiovascular imaging, research designs using single-center series and registries have contributed key foundational insights into diagnosis, resource use and cost patterns, and prognosis as derived from practical, “real-world” settings. This review highlights the strengths and limitations of these study designs, provides notable examples, and indicates future directions for research.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:1936-878X
1876-7591
DOI:10.1016/j.jcmg.2017.01.003