Long-term outcome of antenatally diagnosed agenesis of corpus callosum and cerebellar malformations

Summary Recent advancements in fetal imaging and antenatal care have enabled identification of numerous anomalies including agenesis of corpus callosum and posterior fossa abnormalities. One of the important determinants of long-term prognosis in these conditions is the presence of central nervous s...

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Bibliographic Details
Published inSeminars in fetal & neonatal medicine Vol. 17; no. 5; pp. 295 - 300
Main Authors Vasudevan, C, McKechnie, L, Levene, M
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.10.2012
Subjects
Agenesis
Agenesis of Corpus Callosum - diagnostic imaging
Agenesis of Corpus Callosum - embryology
Cerebellum - abnormalities
Cerebellum - diagnostic imaging
Cerebellum - embryology
Corpus callosum
Female
Fetal
Fetus
Humans
Infant
Neonatal and Perinatal Medicine
Newborn
Pregnancy
Ultrasonography, Prenatal - methods
Infant
Agenesis
Fetal
Newborn
Corpus callosum
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Summary:Summary Recent advancements in fetal imaging and antenatal care have enabled identification of numerous anomalies including agenesis of corpus callosum and posterior fossa abnormalities. One of the important determinants of long-term prognosis in these conditions is the presence of central nervous system (CNS) and extra-CNS anomalies. The difficulty in confirming the isolated nature of these conditions antenatally and the lack of clear information regarding long-term prognoses makes it difficult for the clinician to provide accurate information to the parents antenatally. Caring for these families would require input from a multidisciplinary team involving obstetricians, geneticists, neurologists, radiologists and neonatologists.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:1744-165X
1878-0946
DOI:10.1016/j.siny.2012.07.001