Characterizing Human Nasal Airflow Physiologic Variables by Nasal Index

• Published in: Respiratory physiology & neurobiology Vol. 232; pp. 66 - 74
• Main Authors: Patki, Aniruddha, MD, Frank-Ito, Dennis O., PhD
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2016
• Subjects: Adult; Computational fluid dynamics; Computer Simulation; Female; Heat flux; Humans; Hydrodynamics; Male; Medical Education; Models, Biological; Nasal Cavity - diagnostic imaging; Nasal Cavity - physiology; Nasal index; Nasal resistance; Nose - anatomy & histology; Nose - diagnostic imaging; Nose - physiology; Pulmonary/Respiratory; Respiration; Tomography, X-Ray Computed; Wall shear stress; Wall shear stress; Nasal index; Computational fluid dynamics; Nasal resistance; Heat flux
• ISSN: 1569-9048; 1878-1519
• DOI: 10.1016/j.resp.2016.07.004

Highlights • Computational fluid dynamics modeling was used to investigate the relationship between nasal index and airflow related variables, such as nasal resistance, wall shear stress and heat flux. • Computed tomography scans from 16 subjects with anatomically normal nasal cavities were used to investigate the relationship between nasal index and airflow related variables. • Results confirmed prior studies in the literature suggesting that nasal index and nasal resistance are weakly correlated. • Nasal index accounted for 52% of variability in wall shear stress, the most among all airflow related variables investigated. • Subjects with nasal index less than 80 had stronger correlations with wall shear stress and heat flux than those with nasal index greater than 80.