Diagnosis of Peripheral Facial Palsy Associated with Parvovirus B19 Infection by Polymerase Chain Reaction

Human parvovirus B19 (PVB19) infection causes neurological manifestations, including encephalitis, meningitis, and neuropathy, but facial nerve palsy is rare. Moreover, no case of facial nerve palsy related to PVB19 infection that was diagnosed by PCR and serology has been reported. A 19-month-old b...

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Published inCase reports in pediatrics Vol. 2022; pp. 4574640 - 3
Main Authors Fukuta, Taro, Kawano, Yoshihiko, Ikeda, Maiko, Kawada, Jun-ichi, Ito, Yoshinori, Hara, Shinya
Format Journal Article
LanguageEnglish
Published United States Hindawi 10.01.2022
Hindawi Limited
Wiley
Subjects
Antibodies
Antiviral drugs
Blood
Case Report
Case reports
Cytomegalovirus
Epstein-Barr virus
Erythema
Immunoglobulins
Infections
Infectious diseases
Medical diagnosis
Pathogens
Pediatrics
Serology
Viral infections
Virology
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Summary:Human parvovirus B19 (PVB19) infection causes neurological manifestations, including encephalitis, meningitis, and neuropathy, but facial nerve palsy is rare. Moreover, no case of facial nerve palsy related to PVB19 infection that was diagnosed by PCR and serology has been reported. A 19-month-old boy without the medical history developed facial nerve palsy and was treated with prednisolone and valacyclovir. On the 19th day, erythema appeared on his body, and the PVB19-specific IgM and PVB19 DNA were detected in the serum, leading to the diagnosis of infectious erythema associated with PVB19 infection. This case indicates that PVB19 may be one of the causative agents of facial nerve palsy.
Bibliography:Academic Editor: Ozgur Kasapcopur
ISSN:2090-6803
2090-6811
DOI:10.1155/2022/4574640