Evidence-Based Review of Clinical Studies on Trauma

Clinical studies on trauma represent an important example of the ethical limitations of clinical research because patients cannot be randomized to "trauma" and "no trauma" groups. Instead, this important area of research includes preclinical studies, permitting more comprehensive...

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Bibliographic Details
Published inJournal of endodontics Vol. 35; no. 8; pp. 1160 - 1162
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.08.2009
Subjects
Adjuvants, Immunologic - therapeutic use
Dental Enamel Proteins - therapeutic use
Dentistry
Endocrinology & Metabolism
Evidence-Based Dentistry
Humans
Pilot Projects
Randomized Controlled Trials as Topic
Root Canal Therapy - methods
Root Resorption - prevention & control
Thymosin - analogs & derivatives
Thymosin - therapeutic use
Tooth Avulsion - surgery
Tooth Replantation
Treatment Outcome
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Summary:Clinical studies on trauma represent an important example of the ethical limitations of clinical research because patients cannot be randomized to "trauma" and "no trauma" groups. Instead, this important area of research includes preclinical studies, permitting more comprehensive experimental designs, case series/retrospective studies, and randomized studies in which the intervention focuses on treatment delivered after occurrence of dental trauma.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:0099-2399
1878-3554
1878-3554
DOI:10.1016/j.joen.2009.05.011