Hemigraphis alternata Leaf Extract Incorporated Agar/Pectin-Based Bio-Engineered Wound Dressing Materials for Effective Skin Cancer Wound Care Therapy

• Published in: Polymers Vol. 15; no. 1; p. 115
• Main Authors: Koshy, Jijo, Sangeetha, Dhanaraj
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 27.12.2022; MDPI
• Subjects: agar/pectin; Anticancer properties; Antiinfectives and antibacterials; Antimicrobial agents; Biocompatibility; Biodegradability; Biodegradable materials; Bioengineering; Biological materials; Biomedical materials; Biopolymers; Cancer therapies; Cell cycle; Hemigraphis alternata; Melanoma; Morphology; Pathogens; Pectin; Skin cancer; SKMEL-26 cancer cells; solution casting; Tissue engineering; Wound healing; wound therapy; India; Hemigraphis alternata; agar/pectin; biopolymers; solution casting; SKMEL-26 cancer cells; wound therapy
• ISSN: 2073-4360; 2073-4360
• DOI: 10.3390/polym15010115

The rapidly expanding area of regenerative medicine may soon enter a new phase owing to developments in biomaterials and their application in generating new tissues. Chemicals and synthetic drugs are currently the subject of heated debate due to their effects on human health and the environment. Therefore, scientists seek out new products and procedures that are harmless to both the environment and human health concerns. Bio-based materials provide excellent functional qualities with a variety of applications. This study resulted in the development of a film with antimicrobial, hydrophilic, and anti-cancer properties, which is most beneficial in the medical sectors. In this study, we developed a blended biodegradable film containing agar and pectin (AP), with excellent surface functional properties framed through a casting technique. Additionally, the property can be changed by the addition of extract of (HA) extract. The incorporation of extract in AP (APH) can be used for anti-cancer wound care therapy. The fabricated film is biodegradable, biocompatible, and non-toxic. This material is entirely based on a green methodology, and it was prepared in a concise manner without the use of any hazardous solvents. Based on the overall nature of biopolymer, the prepared material is a promising alternative to our society.