Perfusion MRI may facilitate the diagnosis of a tumefactive demyelinating lesion

[1] Certain conventional magnetic resonance imaging (MRI) features, including a relative lack of mass effect, less substantial perifocal edema, vessel traversing through the lesion, and an open ring enhancement may suggest the diagnosis of tumefactive demyelinating lesions (TDL) with a high degree o...

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Published inNeurology India Vol. 67; no. 3; pp. 908 - 910
Main Authors Naik, Suprava, Bhoi, Sanjeev, Agarwal, Vivek, Kumar, Sunil, Phadke, Rajendra
Format Journal Article
LanguageEnglish
Published India Wolters Kluwer India Pvt. Ltd 01.05.2019
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Subjects
Adult
Blood
Brain Edema - diagnostic imaging
Brain Edema - pathology
Demyelinating Diseases - diagnostic imaging
Diffusion Magnetic Resonance Imaging
Edema
Female
Frontal Lobe - diagnostic imaging
Frontal Lobe - pathology
Glioma
Humans
Lymphoma
Metastasis
NMR
Nuclear magnetic resonance
Tumors
Young Adult
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Summary:[1] Certain conventional magnetic resonance imaging (MRI) features, including a relative lack of mass effect, less substantial perifocal edema, vessel traversing through the lesion, and an open ring enhancement may suggest the diagnosis of tumefactive demyelinating lesions (TDL) with a high degree of certainty. The anti-phospholipid Ab profile revealed the anti-beta-2 glycoprotein 1 (GP1) <3.0 AU/ml, anti-cardiolipin antibody (ACLA IgG)-3.3 GP1/ml, and IgM-5.3 mpl/ml. High-grade gliomas are characterized by the presence of neoangiogenesis and vascular endothelial proliferation and show a high regional cerebral blood flow r(CBF) and regional cerebral blood volume r(CBV).
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.263196