Disseminated T-cell lymphoma in a Brazilian porcupine (Coendou prehensilis)

The current study describes the clinical, gross, histopathologic, and immunohistochemical findings of a T-cell lymphoma in a captive porcupine (Coendou prehensilis), a species typically seen in the tropical forests of Brazil. At necropsy, extensive neoplastic involvement was observed in the cervical...

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Bibliographic Details
Published inJournal of veterinary diagnostic investigation Vol. 23; no. 1; pp. 132 - 135
Main Authors Araujo, Marina Rios de, Luppi, Marcela Miranda, Malta, Marcelo de Campos Cordeiro, Assumpcao, Anna Luiza Facchetti Vinhaes, Langohr, Ingeborg Maria, Ecco, Roselene
Format Journal Article
LanguageEnglish
Published United States 2011
Subjects
Animals
Fatal Outcome
Immunohistochemistry - veterinary
kidneys
liver
lymph nodes
lymphoma
Lymphoma, T-Cell - pathology
Lymphoma, T-Cell - veterinary
Male
Porcupines
Rodent Diseases - pathology
salivary glands
spleen
tropical forests
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Summary:The current study describes the clinical, gross, histopathologic, and immunohistochemical findings of a T-cell lymphoma in a captive porcupine (Coendou prehensilis), a species typically seen in the tropical forests of Brazil. At necropsy, extensive neoplastic involvement was observed in the cervical lymph nodes, with extension into the salivary gland. The spleen was mildly enlarged, and neoplastic nodules were grossly evident in the liver and right kidney. Histologically, sheets of large and markedly pleomorphic round cells were observed in the cervical lymph nodes, lung, liver, spleen, and kidney. The neoplastic cells were positive for cluster of differentiation (CD)3 and negative for CD79a by immunohistochemistry.
ISSN:1040-6387
1943-4936
DOI:10.1177/104063871102300124