Self-Spreading of Lipid Bilayer on a Hydrophobic Surface Made by Self-Assembled Monolayer with Short Alkyl Chain

Behaviors of self-spreading of lipid bilayer membrane on a glass surface modified with self-assembled monolayer (SAM) with short alkyl chain were observed with fluorescence microscopy. Hydrophobic surface made by SAM was found to hamper the self-spreading phenomenon but the lipid bilayer spread on a...

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Bibliographic Details
Published inJournal of nanoscience and nanotechnology Vol. 16; no. 4; p. 3426
Main Authors Omori, Yuya, Sakaue, Hiroyuki, Takahagi, Takayuki, Suzuki, Hitoshi
Format Journal Article
LanguageEnglish
Published United States 01.04.2016
Subjects
Adsorption
Alkylating Agents - chemistry
Crystallization - methods
Glass - chemistry
Hydrophobic and Hydrophilic Interactions
Materials Testing
Nanoparticles - chemistry
Nanoparticles - ultrastructure
Surface Properties
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Summary:Behaviors of self-spreading of lipid bilayer membrane on a glass surface modified with self-assembled monolayer (SAM) with short alkyl chain were observed with fluorescence microscopy. Hydrophobic surface made by SAM was found to hamper the self-spreading phenomenon but the lipid bilayer spread on a hydrophilic one where SAM was decomposed by oxidation. On a binary surface having a hydrophobic region and a hydrophilic one, the lipid bilayer spread on the hydrophilic region but it stopped at the boundary of the hydrophobic region.
ISSN:1533-4880
DOI:10.1166/jnn.2016.12307