Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA

Two novel macrocyclic polyamine ligands and their dinuclear zinc (II)complexes were synthesized and characterized. Their interaction with plasmid DNA wasstudied by gel electrophoresis and fluorescence quenching experiment. The result showedthat these complexes could bind DNA efficiently under physio...

Full description

Saved in:
Bibliographic Details
Published inInternational journal of molecular sciences Vol. 8; no. 7; pp. 606 - 617
Main Authors Huang, Jun, Huang, Qing-Dong, Zhang, Ji, Zhou, Li-Hong, Li, Qiang-Lin, Li, Kun, Jiang, Ning, Lin, Hong-Hui, Wu, Jiang, Yu, Xiao-Qi
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.07.2007
Molecular Diversity Preservation International (MDPI)
Subjects
1,4,7,10-tetraazacyclododecane (cyclen)
DNA protection
Full Research Paper
imidazolium
Ligands
Nanoparticles
Polyamines
synthesis
Zinc
zinc (II) complexes
China
Online AccessGet full text

Cover

More Information
Summary:Two novel macrocyclic polyamine ligands and their dinuclear zinc (II)complexes were synthesized and characterized. Their interaction with plasmid DNA wasstudied by gel electrophoresis and fluorescence quenching experiment. The result showedthat these complexes could bind DNA efficiently under physiological conditions.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/i8070606