Diabetic nephropathy in the elderly

Although diabetes is clearly linked to macro- and microvasculopathy in multiple organs resulting in cardiovascular and cerebrovascular catastrophic diseases, blindness, and limb amputations, it is the relentless progression of diabetic nephropathy toward becoming the major cause of end-stage renal d...

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Bibliographic Details
Published inClinics in geriatric medicine Vol. 25; no. 3; p. 373
Main Authors Joseph, Anthony J, Friedman, Eli A
Format Journal Article
LanguageEnglish
Published United States 01.08.2009
Subjects
Age Factors
Aged
Biopsy
Diabetic Nephropathies - epidemiology
Diabetic Nephropathies - physiopathology
Diabetic Nephropathies - therapy
Diet, Protein-Restricted - methods
Disease Progression
Global Health
Glomerular Filtration Rate
Humans
Hypoglycemic Agents - therapeutic use
Life Style
Morbidity
Prognosis
Renal Replacement Therapy - methods
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Summary:Although diabetes is clearly linked to macro- and microvasculopathy in multiple organs resulting in cardiovascular and cerebrovascular catastrophic diseases, blindness, and limb amputations, it is the relentless progression of diabetic nephropathy toward becoming the major cause of end-stage renal disease (ESRD) that now challenges budgets and treatment facilities providing hemodialysis, peritoneal dialysis, and kidney transplantation. Nephrology, as a specialty, is now dominated by the necessity to address geriatrics and endocrinology to cope with the tidal wave of elderly ESRD patients suffering from uremia caused by diabetes. On the brighter side, emergence of effective renoprotective regimens now slow the incidence rate of ESRD in those with diagnosed diabetes. There is bona fide reason to hope that within a decade, kidney failure attributable to diabetes will be transformed into a preventable complication of a disease that has dominated and directed our heritage.
ISSN:1879-8853
DOI:10.1016/j.cger.2009.06.005