A novel somatic mutation 145-147delETEinsK in KCNJ5 increases aldosterone production

• Published in: Journal of human hypertension Vol. 31; no. 11; pp. 756 - 759
• Main Authors: Zheng, F-F, Zhu, L-M, Zhou, W-L, Zhang, Y, Li, M-Y, Zhu, Y-C, Wang, J-G, Zhu, D-L, Gao, P-J
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 01.11.2017
• Subjects: Adrenal Cortex Neoplasms - blood; Adrenal Cortex Neoplasms - complications; Adrenal Cortex Neoplasms - diagnosis; Adrenal Cortex Neoplasms - genetics; Adrenal glands; Adrenocortical Adenoma - blood; Adrenocortical Adenoma - complications; Adrenocortical Adenoma - diagnosis; Adrenocortical Adenoma - genetics; Aldosterone; Aldosterone - blood; Biomarkers, Tumor - genetics; Biomarkers, Tumor - metabolism; Calcium - metabolism; Care and treatment; Conflicts of interest; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels - genetics; G Protein-Coupled Inwardly-Rectifying Potassium Channels - metabolism; Gene mutation; Genetic aspects; Genetic Predisposition to Disease; HEK293 Cells; Hospitals; Humans; Hyperaldosteronism - blood; Hyperaldosteronism - diagnosis; Hyperaldosteronism - etiology; Hyperaldosteronism - genetics; Hypertension; Laboratories; Medicine; Membrane Potentials; Mutation; Patients; Phenotype; Potassium; Potassium - metabolism; Signal transduction; Sodium - metabolism; Transfection; Tumors; Urology
• ISSN: 0950-9240; 1476-5527
• DOI: 10.1038/jhh.2017.50