Guidelines on nuclear medicine imaging in neuroblastoma

• Published in: European journal of nuclear medicine and molecular imaging Vol. 45; no. 11; pp. 2009 - 2024
• Main Authors: Bar-Sever, Zvi, Biassoni, Lorenzo, Shulkin, Barry, Kong, Grace, Hofman, Michael S., Lopci, Egesta, Manea, Irina, Koziorowski, Jacek, Castellani, Rita, Boubaker, Ariane, Lambert, Bieke, Pfluger, Thomas, Nadel, Helen, Sharp, Susan, Giammarile, Francesco
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.10.2018; Springer Nature B.V
• Subjects: Cardiology; Children; Computed tomography; Dihydroxyphenylalanine; Fluorine isotopes; Guidelines; Imaging; Medical imaging; Medicine; Medicine & Public Health; Neuroblastoma; Nuclear Medicine; Oncology; Orthopedics; Peptides; Positron emission; Positron emission tomography; Radiology; Tomography; Tumors; Ga-DOTA TATE PET/CT; I-MIBG; F-FDG PET/CT; F-DOPA PET/CT; Neuroblastoma; Children; Guidelines; 18F-FDG PET/CT; 123I-MIBG; 68Ga-DOTA TATE PET/CT; 18F-DOPA PET/CT; Ga-68-DOTA TATE PET; F-18-FDG PET; CT; F-18-DOPA PET; I-123-MIBG
• ISSN: 1619-7070; 1619-7089; 1619-7089
• DOI: 10.1007/s00259-018-4070-8

Nuclear medicine has a central role in the diagnosis, staging, response assessment and long-term follow-up of neuroblastoma, the most common solid extracranial tumour in children. These EANM guidelines include updated information on 123 I-mIBG, the most common study in nuclear medicine for the evaluation of neuroblastoma, and on PET/CT imaging with 18 F-FDG, 18 F-DOPA and 68 Ga-DOTA peptides. These PET/CT studies are increasingly employed in clinical practice. Indications, advantages and limitations are presented along with recommendations on study protocols, interpretation of findings and reporting results.