Metabolism and biochemistry in hypogravity
The headward shift of body fluid and increase in stress-related hormones that occur in hypogravity bring about a number of changes in metabolism and biochemistry of the human body. Such alterations may have important effects on health during flight and during a recovery period after return to Earth....
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Published in | Acta astronautica Vol. 23; pp. 105 - 108 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
Legacy CDMS
Elsevier Ltd
1991
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Subjects | |
Online Access | Get full text |
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Summary: | The headward shift of body fluid and increase in stress-related hormones that occur in hypogravity bring about a number of changes in metabolism and biochemistry of the human body. Such alterations may have important effects on health during flight and during a recovery period after return to Earth. Body fluid and electrolytes are lost, and blood levels of several hormones that control metabolism are altered during space flight. Increased serum calcium may lead to an increased risk of renal stone formation during flight, and altered drug metabolism could influence the efficacy of therapeutic agents. Orthostatic intolerance and an increased risk of fracturing weakened bones are concerns at landing. It is important to understand biochemistry and metabolism in hypogravity so that clinically important developments can be anticipated and prevented or ameliorated. |
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Bibliography: | CDMS Legacy CDMS SourceType-Scholarly Journals-2 ObjectType-Feature-2 ObjectType-Conference Paper-1 content type line 23 SourceType-Conference Papers & Proceedings-1 ObjectType-Article-3 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 ObjectType-Review-1 |
ISSN: | 0094-5765 1879-2030 |
DOI: | 10.1016/0094-5765(91)90105-E |