Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Polyoxometalates (PMs) as discrete metal-oxide cluster anions comprise a versatile class of inorganic, anionic clusters that have a wide variety of structures, sizes, and a combination of metals, high solubility in water, and electrochemical activity. Recent investigation of anti-tumor, -viral, and...
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| Published in | Journal of Materials Chemistry Vol. 15; no. 45; p. 4773 |
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| Main Author | |
| Format | Web Resource |
| Language | English |
| Published |
Cambridge
Royal Society of Chemistry
07.12.2005
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| Online Access | Get full text |
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| Summary: | Polyoxometalates (PMs) as discrete metal-oxide cluster anions comprise a versatile class of inorganic, anionic clusters that have a wide variety of structures, sizes, and a combination of metals, high solubility in water, and electrochemical activity. Recent investigation of anti-tumor, -viral, and -bacterial activities of PMs shows induced cell-apoptosis, inhibition of binding of virus to receptor, and the enhancement of β-lactam antibiotics as well as the inhibition of bacterial growth, respectively. PMs exemplified for each biological activity are discussed from the chemotherapeutic point of view for the establishment of a novel inorganic drug based on PMs. |
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| DOI: | 10.1039/B504585A |