Trends in postpartum hemorrhage: United States, 1994–2006

• Published in: American journal of obstetrics and gynecology Vol. 202; no. 4; pp. 353.e1 - 353.e6
• Main Authors: Callaghan, William M., MD, MPH, Kuklina, Elena V., MD, PhD, Berg, Cynthia J., MD, MPH
• Format: Journal Article
• Language: English
• Published: United States Mosby, Inc 01.04.2010
• Subjects: Adult; Cesarean Section - statistics & numerical data; Databases, Factual; Diabetes, Gestational - epidemiology; Female; Humans; Hypertension, Pregnancy-Induced - epidemiology; Incidence; Logistic Models; Maternal Age; Multivariate Analysis; Obstetrics and Gynecology; Parity; postpartum hemorrhage; Postpartum Hemorrhage - epidemiology; Pregnancy; United States - epidemiology; uterine atony; Uterine Inertia - epidemiology; Young Adult; United States; postpartum hemorrhage; pregnancy; uterine atony
• ISSN: 0002-9378; 1097-6868
• DOI: 10.1016/j.ajog.2010.01.011

Objective The purpose of this study was to estimate the incidence of postpartum hemorrhage (PPH) in the United States and to assess trends. Study Design Population-based data from the 1994–2006 National Inpatient Sample were used to identify women who were hospitalized with postpartum hemorrhage. Data for each year were plotted, and trends were assessed. Multivariable logistic regression was used in an attempt to explain the difference in PPH incidence between 1994 and 2006. Results PPH increased 26% between 1994 and 2006 from 2.3% (n = 85,954) to 2.9% (n = 124,708; P < .001). The increase primarily was due to an increase in uterine atony, from 1.6% (n = 58,597) to 2.4% (n = 99,904; P < .001). The increase in PPH could not be explained by changes in rates of cesarean delivery, vaginal birth after cesarean delivery, maternal age, multiple birth, hypertension, or diabetes mellitus. Conclusion Population-based surveillance data signal an apparent increase in PPH caused by uterine atony. More nuanced clinical data are needed to understand the factors that are associated with this trend.