Diffusion and Antibacterial Properties of Nisin-Loaded Chitosan/Poly (L-Lactic Acid) Towards Development of Active Food Packaging Film
Nisin-loaded chitosan/poly (L-lactic acid) (nisin-CS/PLLA) antimicrobial films were prepared by coating method. The structure and mechanical properties of nisin carrier CS/PLLA films were investigated, and the antibacterial behavior of nisin-CS/PLLA against Staphylococcus aureus ATCC6538 was assesse...
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Published in | Food and bioprocess technology Vol. 8; no. 8; pp. 1657 - 1667 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
New York
Springer US
01.08.2015
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
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Summary: | Nisin-loaded chitosan/poly (L-lactic acid) (nisin-CS/PLLA) antimicrobial films were prepared by coating method. The structure and mechanical properties of nisin carrier CS/PLLA films were investigated, and the antibacterial behavior of nisin-CS/PLLA against Staphylococcus aureus ATCC6538 was assessed. Furthermore, the diffusion behaviors of nisin from films were evaluated by diffusion kinetics and thermodynamics, and the diffusion efficiency was investigated as a function of CS/PLLA ratio, pH, and ionic strength. When CS/PLLA ratio was at 1:1 (w/w) and above, a notable enhancement was observed in the tensile strength with the increase of PLLA content, while the elongation at break was decreased slightly at the same time. However, a significant decrease in tensile strength and elongation at break were present when the CS/PLLA ratio was below 1:1. There existed intermolecular hydrogen bonds between CS and PLLA molecules. The diffusion of nisin from film was strongly dependent on pH and ionic strength. The thermodynamic parameters (ΔH ᵒ , ΔS ᵒ , and ΔG ᵒ) indicated that the diffusion process of nisin from film was spontaneous and endothermic. From diffusion and antimicrobial activity results, nisin-CS/PLLA films revealed well-controlled release and better antimicrobial activity against S. aureus, which may have potential as a novel active food packaging film. |
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Bibliography: | http://dx.doi.org/10.1007/s11947-015-1522-z |
ISSN: | 1935-5130 1935-5149 |
DOI: | 10.1007/s11947-015-1522-z |