Anti-inflammatory activity of Euphorbia acaulis Roxb

From various extracts of Euphorbia acaulis , the n-hexane fraction showed marked anti-inflammatory activity in carrageenan induced oedema in rats and mice as compared to phenylbutazone and was equipotent in adrenal- ectomised rats. In chronic models of formaldehyde and adjuvant arthritis, its anti-a...

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Bibliographic Details
Published inJournal of ethnopharmacology Vol. 10; no. 2; pp. 225 - 233
Main Authors Singh, G.B, Kaur, S, Satti, N.K, Atal, C.K, Maheshweri, J.K
Format Journal Article
LanguageEnglish
Published Ireland 01.01.1984
Subjects
Analgesics - pharmacology
Animals
Anti-Inflammatory Agents - pharmacology
Arthritis - drug therapy
Carrageenan
Diuretics - pharmacology
Edema - drug therapy
India
Male
Mice
Plant Extracts - pharmacology
Plants, Medicinal
Rats
India
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Summary:From various extracts of Euphorbia acaulis , the n-hexane fraction showed marked anti-inflammatory activity in carrageenan induced oedema in rats and mice as compared to phenylbutazone and was equipotent in adrenal- ectomised rats. In chronic models of formaldehyde and adjuvant arthritis, its anti-arthritic activity was found to be superior to that of phenylbutazone. It had a diuretic effect but did not show any analgesic or antipyretic activity.
ISSN:0378-8741
1872-7573
DOI:10.1016/0378-8741(84)90004-7