Integration of capillary-hydrodynamic logic circuitries for built-in control over multiple droplets in microfluidic networks
Here, we show the successful implementation of advanced sequential logic in droplet microfluidics, whose principles rely on capillary wells establishing stationary states, where droplets can communicate remotely via pressure impulses, influencing each other and switching the device states. All logic...
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Published in | Lab on a chip Vol. 21; no. 9; pp. 1771 - 1778 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
England
Royal Society of Chemistry
04.05.2021
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Subjects | |
Online Access | Get full text |
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Summary: | Here, we show the successful implementation of advanced sequential logic in droplet microfluidics, whose principles rely on capillary wells establishing stationary states, where droplets can communicate remotely
via
pressure impulses, influencing each other and switching the device states. All logic operations perform spontaneously due to the utilization of nothing more than capillary-hydrodynamic interactions, inherent for the confined biphasic flow. Our approach offers integration feasibility allowing to encode unprecedentedly long algorithms,
e.g.
, 1000-droplet counting. This work has the potential for the advancement of liquid computers and thereby could participate in the development of the next generation of portable microfluidic systems with embedded control, enabling applications from single-cell analysis and biochemical assays to materials science.
Passive integrated microfluidic logic structures allowing for the microelectronics-inspired programming of operations on sequences of droplets. |
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Bibliography: | 10.1039/d0lc00900h Electronic supplementary information (ESI) available: Supplementary notes, supplementary movies and list of supplementary movies. See DOI ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1473-0197 1473-0189 |
DOI: | 10.1039/d0lc00900h |