Echocardiographic Evaluation of Right Ventricular (RV) Performance over Time in COVID-19-Associated ARDS—A Prospective Observational Study

(1) Background: To evaluate time-dependent right ventricular (RV) performance in patients with COVID-19-associated acute respiratory distress syndrome (ARDS) undergoing intensive care (ICU) treatment. (2) Methods: This prospective observational study included 21 ICU patients with COVID-19-associated...

Full description

Saved in:
Bibliographic Details
Published inJournal of clinical medicine Vol. 10; no. 9; p. 1944
Main Authors Asgarpur, Golschan, Treskatsch, Sascha, Angermair, Stefan, Danassis, Michaela, Nothnagel, Anna Maria, Toepper, Christoph, Trauzeddel, Ralf Felix, Nordine, Michael, Heeschen, Julia, Al-Chehadeh, Alaa, Landmesser, Ulf, Sander, Leif Erik, Kurth, Florian, Berger, Christian
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.05.2021
MDPI
Subjects
ARDS
Clinical medicine
Coronaviruses
COVID-19
Edema
Human papillomavirus
Intensive care
Laboratories
Mortality
Observational studies
Patients
Pulmonary hypertension
Regression analysis
RV function
Severe acute respiratory syndrome coronavirus 2
transthoracic echocardiography
Ventilators
United States > US
Germany
Chicago Illinois
Online AccessGet full text

Cover

More Information
Summary:(1) Background: To evaluate time-dependent right ventricular (RV) performance in patients with COVID-19-associated acute respiratory distress syndrome (ARDS) undergoing intensive care (ICU) treatment. (2) Methods: This prospective observational study included 21 ICU patients with COVID-19-associated ARDS in a university hospital in 2020 (first wave). Patients were evaluated by transthoracic echocardiography at an early (EE) and late (LE) stage of disease. Echocardiographic parameters describing RV size and function as well as RV size in correlation to PaO2/FiO2 ratio were assessed in survivors and nonsurvivors. (3) Results: Echocardiographic RV parameters were within normal range and not significantly different between EE and LE. Comparing survivors and nonsurvivors revealed no differences in RV performance at EE. Linear regression analysis did not show a correlation between RV size and PaO2/FiO2 ratio over all measurements. Analysing EE and LE separately showed a significant increase in RV size correlated to a lower PaO2/FiO2 ratio at a later stage of COVID-19 ARDS. (4) Conclusion: The present study reveals neither a severe RV dilatation nor an impairment of systolic RV function during the initial course of COVID-19-associated ARDS. A trend towards an increase in RV size in correlation with ARDS severity in the second week after ICU admission was observed.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
These authors contributed equally.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm10091944