Exclusive Breastfeeding Is Inversely Associated with Risk of Childhood Overweight in a Large Chinese Cohort

• Published in: The Journal of nutrition Vol. 144; no. 9; pp. 1454 - 1459
• Main Authors: Zheng, Ju-Sheng, Liu, Huijuan, Li, Jing, Chen, Yu, Wei, Chunlei, Shen, Genmei, Zhu, Shanlin, Chen, Hua, Zhao, Yi-Min, Huang, Tao, Li, Duo
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Elsevier Inc 01.09.2014; American Society for Nutrition
• Subjects: Biological and medical sciences; Body Mass Index; Breast Feeding; Child, Preschool; China; Cohort Studies; Feeding. Feeding behavior; Female; Fundamental and applied biological sciences. Psychology; Humans; Infant; Infant, Newborn; Male; Medical sciences; Metabolic diseases; Obesity; Overweight - prevention & control; Pediatric Obesity - prevention & control; Risk; Sex Factors; Vertebrates: anatomy and physiology, studies on body, several organs or systems; China; Human; Chinese; Nutrition; Child; Risk factor; Overweight
• ISSN: 0022-3166; 1541-6100
• DOI: 10.3945/jn.114.193664

The association between breastfeeding status and childhood overweight is inconclusive. The aim of the present study was to investigate the relation between exclusive breastfeeding and childhood overweight risk in children 4–5 y of age in Southeast China. Among 97,424 children enrolled between 1999 and 2009 in the Jiaxing Birth Cohort, 42,550 of them were included in the final analysis with complete records on breastfeeding status and anthropometric measurements at 4–5 y of age (48–60 mo). Overweight and being at risk of overweight were identified as a body mass index (BMI)-for-age Z-score ≥ 2 and between 1 and 2, respectively. After 4–5 y of follow-up, 4845 (11.4%) children were identified as being at risk of overweight, and 1343 (3.16%) children were overweight. Adjusting for important child and maternal characteristics, longer duration of breastfeeding was associated with lower risk of childhood overweight (P-trend = 0.009) and being at risk of overweight (P-trend < 0.001). Children exclusively breastfed for 3–5 mo and ≥6 mo had 13% (RR = 0.87; 95% CI: 0.77, 0.99) and 27% (RR = 0.73; 95% CI: 0.56, 0.95) lower risk of becoming overweight compared with children exclusively breastfed for <1 mo, respectively. In boys, there were inverse associations of 3–5 mo (RR = 0.83; 95% CI: 0.71, 0.98) or ≥6 mo (RR = 0.65; 95% CI: 0.47, 0.91) of exclusive breastfeeding against becoming overweight, but there were no significant associations in girls (3–5 mo: RR = 0.96, 95% CI: 0.76, 1.22; ≥6 mo: RR = 0.92, 95% CI: 0.60, 1.41). In conclusion, the present findings suggest that longer duration of exclusive breastfeeding is associated with lower risk of becoming overweight in Chinese children.