Case report: lenvatinib in neoadjuvant setting in a patient affected by invasive poorly differentiated thyroid carcinoma

• Published in: Future oncology (London, England) Vol. 15; no. 24s; pp. 13 - 19
• Main Authors: Gay, Stefano, Monti, Eleonora, Trambaiolo Antonelli, Chiara, Mora, Marco, Spina, Bruno, Ansaldo, Gianluca, Teliti, Marsida, Comina, Martina, Conte, Lucia, Minuto, Michele, Varaldo, Elisabetta, Zupo, Simonetta, Massa, Barbara, Morbelli, Silvia, Giusti, Massimo
• Format: Journal Article
• Language: English
• Published: England Future Medicine Ltd 01.08.2019
• Subjects: Aged, 80 and over; Biopsy; Bronchoscopy; Cancer therapies; Carcinoma, Papillary - diagnostic imaging; Carcinoma, Papillary - drug therapy; Carcinoma, Papillary - pathology; Carcinoma, Papillary - surgery; case report; Case reports; Dyspnea; Female; Humans; Hypotheses; Iodine Radioisotopes - administration & dosage; lenvatinib; Medical prognosis; neoadjuvant; Neoadjuvant Therapy; Phenylurea Compounds - administration & dosage; Quinolines - administration & dosage; Radiation therapy; Surgery; Thromboembolism; Thrombosis; Thyroid cancer; thyroid carcinoma; Thyroid Neoplasms - diagnostic imaging; Thyroid Neoplasms - drug therapy; Thyroid Neoplasms - pathology; Thyroid Neoplasms - surgery; Thyroidectomy; Tumors; Ultrasonic imaging; case report; neoadjuvant; thyroid carcinoma; lenvatinib

We report a case of an elderly woman presenting with a huge cervical mass invading the tracheal lumen. Diagnosed as invasive poorly differentiated thyroid cancer, after an endotracheal biopsy, stenting and radiotherapy, it was judged eligible for total thyroidectomy, but surgery was delayed due to p...