The genetics, biosynthesis and regulation of toxic specialized metabolites of cyanobacteria

The production of toxic metabolites by cyanobacterial blooms represents a significant threat to the health of humans and ecosystems worldwide. Here we summarize the current state of the knowledge regarding the genetics, biosynthesis and regulation of well-characterized cyanotoxins, including the mic...

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Bibliographic Details
Published inHarmful algae Vol. 54; pp. 98 - 111
Main Authors Pearson, Leanne A., Dittmann, Elke, Mazmouz, Rabia, Ongley, Sarah E., D’Agostino, Paul M., Neilan, Brett A.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.04.2016
Subjects
algae
anatoxins
aplysiatoxin
Bacterial Toxins - biosynthesis
Bacterial Toxins - genetics
Bacterial Toxins - metabolism
Biosynthesis
Cyanobacteria
Cyanobacteria - genetics
Cyanobacteria - physiology
Cyanotoxins
cylindrospermopsin
Ecosystem
ecosystems
Gene Expression Regulation, Bacterial
Genetics
Humans
metabolites
microcystins
nodularin
Regulation
saxitoxins
Specialized metabolites
toxicity
Specialized metabolites
Genetics
Biosynthesis
Regulation
Cyanobacteria
Cyanotoxins
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Summary:The production of toxic metabolites by cyanobacterial blooms represents a significant threat to the health of humans and ecosystems worldwide. Here we summarize the current state of the knowledge regarding the genetics, biosynthesis and regulation of well-characterized cyanotoxins, including the microcystins, nodularin, cylindrospermopsin, saxitoxins and anatoxins, as well as the lesser-known marine toxins (e.g. lyngbyatoxin, aplysiatoxin, jamaicamides, barbamide, curacin, hectochlorin and apratoxins).
Bibliography:http://dx.doi.org/10.1016/j.hal.2015.11.002
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1568-9883
1878-1470
DOI:10.1016/j.hal.2015.11.002