THz Exposure of Whole Blood for the Study of Biological Effects on Human Lymphocytes

The aim of the present study is toinvestigate the genotoxic effect of THzradiation in human peripheral bloodlymphocytes following 20 minutes exposureto 1 mW average power Free Electron Laserradiation in the frequency range 120-140GHz. For this purpose 9 healthy donors wereemployed and cytokinesis bl...

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Published inJournal of biological physics Vol. 29; no. 2-3; pp. 171 - 176
Main Authors Scarfì, M R, Romanò, M, Di Pietro, R, Zeni, O, Doria, A, Gallerano, G P, Giovenale, E, Messina, G, Lai, A, Campurra, G, Coniglio, D, D'Arienzo, M
Format Journal Article
LanguageEnglish
Published Netherlands Springer Nature B.V 01.06.2003
Kluwer Academic Publishers
Subjects
Biophysics
Blood
Cytokines
Genomics
Kinetics
Lymphocytes
Cell proliferation
human lymphocytes
THz radiation
micronuclei
genotoxic effects
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Summary:The aim of the present study is toinvestigate the genotoxic effect of THzradiation in human peripheral bloodlymphocytes following 20 minutes exposureto 1 mW average power Free Electron Laserradiation in the frequency range 120-140GHz. For this purpose 9 healthy donors wereemployed and cytokinesis block techniquewas applied to study micronucleusfrequency and cell proliferation. Theresults obtained indicate that all theelectromagnetic conditions adopted so far do not alter the investigated parameters,suggesting absence of direct chromosomaldamage and alteration of cell cyclekinetics (two tailed paired Student's test:p> 0.05 in all cases).
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ISSN:0092-0606
1573-0689
DOI:10.1023/A:1024440708943