Acute mania after thyroxin supplementation in hypothyroid state

The current literature variedly ascribes depressive and manic symptoms to hypo- and hyperthyroid state, respectively, reporting mania in hypothyroidism as an unusual entity. More unusual is precipitation of manic state in hypothyroid subjects after thyroxine supplementation for which studies report...

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Bibliographic Details
Published inIndian journal of endocrinology and metabolism Vol. 17; no. 5; pp. 922 - 923
Main Authors Verma, Rohit, Sachdeva, Ankur, Singh, Yogendra, Balhara, Yatan
Format Journal Article
LanguageEnglish
Published India Medknow Publications 01.09.2013
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt Ltd
Wolters Kluwer Medknow Publications
Subjects
Care and treatment
Case Report
Case studies
Complications and side effects
Diagnosis
Health aspects
Hypothroidism
Hypothyroidism
Mania
Patient outcomes
Risk factors
Thyroxine
thyroxine supplementation
India
Hypothroidism
thyroxine supplementation
mania
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Summary:The current literature variedly ascribes depressive and manic symptoms to hypo- and hyperthyroid state, respectively, reporting mania in hypothyroidism as an unusual entity. More unusual is precipitation of manic state in hypothyroid subjects after thyroxine supplementation for which studies report otherwise treating manic symptoms in hypothyroid state with thyroxine. We report a case of a patient whose acute mania appears to have been precipitated by thyroxine supplementation in hypothyroidism state. This case underscores the importance of thyroid screening in patients with mood and psychotic disorders, as well as the potency of thyroxine in producing manic symptoms.
ISSN:2230-8210
2230-9500
DOI:10.4103/2230-8210.117220