Chemically separated connective tissue grafts: clinical application and histological evaluation

Subepithelial palatal connective tissue grafts, separated from the epithelium either chemically (n = 5) or surgically (n = 2) were inserted in patients presenting with gingival recession. Biopsies at the grafted tissue and a portion of non-keratinized mucosa were taken 12 months later. Histology sho...

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Bibliographic Details
Published inJournal of periodontology (1970) Vol. 64; no. 8; p. 734
Main Authors Ouhayoun, J P, Khattab, R, Serfaty, R, Feghaly-Assaly, M, Sawaf, M H
Format Journal Article
LanguageEnglish
Published United States 01.08.1993
Subjects
Connective Tissue - surgery
Connective Tissue - transplantation
Edetic Acid
Endopeptidases
Epithelium - physiopathology
Gingival Recession - surgery
Humans
Keratins - analysis
Keratins - physiology
Mouth Mucosa - anatomy & histology
Mouth Mucosa - transplantation
Palate - surgery
Surgical Flaps
Tissue Transplantation - methods
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Summary:Subepithelial palatal connective tissue grafts, separated from the epithelium either chemically (n = 5) or surgically (n = 2) were inserted in patients presenting with gingival recession. Biopsies at the grafted tissue and a portion of non-keratinized mucosa were taken 12 months later. Histology showed keratinization of the newly formed epithelium, and interestingly a deep projection of epithelium into the connective tissue in almost all biopsies, sometimes with an enlargement and a cyst-like space. We conclude that chemical separation of epithelium and connective tissue is clinically feasible for connective tissue grafts and that the subepithelial connective tissue grafting technique should be modified to avoid this projection of epithelium.
ISSN:0022-3492
DOI:10.1902/jop.1993.64.8.734