Calculating arterial pressure-based cardiac output using a novel measurement and analysis method

Work on applying physical and physiological principles for determining cardiac output by analysis of pressure measurements has been pursued for decades. Reference measurements for this kind of cardiac output analysis rely on the pulmonary artery catheter (PAC), considered the clinical gold standard...

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Bibliographic Details
Published inBiomedical instrumentation & technology Vol. 41; no. 5; pp. 403 - 411
Main Authors Pratt, Benjamin, Roteliuk, Luchy, Hatib, Feras, Frazier, John, Wallen, Roy D
Format Journal Article
LanguageEnglish
Published United States Association for the Advancement of Medical Instrumentation, AAMI 01.09.2007
Subjects
Algorithms
Automatic Data Processing
Blood Pressure - physiology
Blood Pressure Monitors - trends
Calibration
Cardiac Output - physiology
Catheters
Compliance
Critical care
Heart rate
Hemodynamics
Humans
Hydraulics
Models, Cardiovascular
Monitoring, Physiologic - methods
Patients
Pattern Recognition, Automated
Physiology
Pulmonary arteries
Reproducibility of Results
Sensors
Signal Processing, Computer-Assisted
Veins & arteries
Waveform analysis
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Summary:Work on applying physical and physiological principles for determining cardiac output by analysis of pressure measurements has been pursued for decades. Reference measurements for this kind of cardiac output analysis rely on the pulmonary artery catheter (PAC), considered the clinical gold standard for cardiac output monitoring. Recent advances in signal processing, as well as applied information on the relationships that enable arterial pulse pressure to be used to determine stroke volume, have led to the development of a novel system that can continuously measure cardiac output from an arterial pressure waveform that does not require an external calibration reference method. There are significant challenges in applying statistical- and signal-processing practices to the analysis of complex physiological waveforms. This paper reviews the historical basis for measuring flow from the analysis of pressure in a vessel, establishes the physiological and mathematical basis for this new system and describes its performance under various physiological conditions.
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ISSN:0899-8205
1943-5967
DOI:10.2345/0899-8205(2007)41[403:capcou]2.0.co;2