The effects of graded exercise on plasma proenkephalin peptide F and catecholamine responses at sea level

• Published in: European journal of applied physiology and occupational physiology Vol. 61; no. 3-4; p. 214
• Main Authors: Kraemer, W J, Dziados, J E, Gordon, S E, Marchitelli, L J, Fry, A C, Reynolds, K L
• Format: Journal Article
• Language: English
• Published: Germany 01.10.1990
• Subjects: Adult; Enkephalin, Methionine - analogs & derivatives; Enkephalin, Methionine - blood; Epinephrine - blood; Exercise - physiology; Humans; Kinetics; Lactates - blood; Lactic Acid; Male; Norepinephrine - blood; Oxygen Consumption; Protein Precursors - blood
• ISSN: 0301-5548
• DOI: 10.1007/bf00357602

The purpose of this study was to evaluate the effects of graded treadmill exercise on plasma preproenkephalin peptide F immunoreactivity and concomitant catecholamine responses at sea level (elevation, 50 m). Few data exist regarding the sea-level responses of plasma peptide F immunoreactivity to exercise. thirty-five healthy men performed a graded exercise test on a motor-driven treadmill at the relative exercise intensities of 25, 50, 75, and 100% of maximum oxygen consumption (VO2max). Significant (P less than 0.05) increases above rest were observed for plasma peptide F immunoreactivity and norepinephrine at 75 and 100% of the VO2 max and at 5 min into recovery. Significant increases in plasma epinephrine were observed at 75 and 100% of VO2max. Whole blood lactate significantly increased above resting values at 50, 75, and 100% of the VO2max and at 5 min into recovery. These data demonstrate that exercise stress increases plasma peptide F immunoreactivity levels at sea level. While the exercise response patterns of peptide F immunoreactivity are similar to catecholamines and blood lactate responses, no bivariate relationships were observed. These data show that sea-level response patterns to graded exercise are similar to those previously observed at moderate altitude (elevation, 2200 m).