Predictive value of early second trimester maternal serum cyclophilin A concentrations in women complicated with preeclampsia: a preliminary case-control study

To investigate cyclophilin A in early second trimester of pregnancy before the onset of preeclampsia. In this prospective case-control study, 51 pregnant women whose serum were collected and stored and who developed preeclampsia in later follow-up and 41 pregnant women as control group were included...

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Published inHypertension in pregnancy Vol. 39; no. 4; pp. 387 - 392
Main Authors Celik, Samettin, Soyer Çalışkan, Canan
Format Journal Article
LanguageEnglish
Published Taylor & Francis 01.10.2020
Taylor & Francis Group
Subjects
cyclophilin A
gestational hypertension
predictive models
preeclampsia
Pregnancy
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Summary:To investigate cyclophilin A in early second trimester of pregnancy before the onset of preeclampsia. In this prospective case-control study, 51 pregnant women whose serum were collected and stored and who developed preeclampsia in later follow-up and 41 pregnant women as control group were included. Maternal serum cyclophilin A levels in the study group who developed preeclampsia in later follow-up were significantly higher than those of normal healthy pregnant women. Cyclophilin A may be a valuable predictor for pregnant women who subsequently develop preeclampsia in their pregnancies.
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ISSN:1064-1955
1525-6065
DOI:10.1080/10641955.2020.1777301