Clostridium cadaveris Septic Arthritis after Total Hip Arthroplasty in a Metastatic Breast Cancer Patient

• Published in: The Journal of arthroplasty Vol. 22; no. 2; pp. 289 - 292
• Main Authors: Morshed, Saam, MD, MPH, Malek, Farbod, MD, Silverstein, Robert M., MD, O'Donnell, Richard J., MD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2007
• Subjects: Acetabulum - pathology; Acetabulum - surgery; Anti-Infective Agents - therapeutic use; Arthritis, Infectious - microbiology; Arthritis, Infectious - therapy; Arthroplasty, Replacement, Hip; Bone Neoplasms - secondary; Bone Neoplasms - surgery; Breast Neoplasms - pathology; Clostridium cadaveris; Clostridium Infections - microbiology; Clostridium Infections - therapy; Debridement; Fatal Outcome; Female; Humans; malignancy; Middle Aged; Orthopedics; prosthesis retention; sepsis; total hip arthroplasty; total hip arthroplasty; Clostridium cadaveris; malignancy; prosthesis retention; sepsis
• ISSN: 0883-5403; 1532-8406
• DOI: 10.1016/j.arth.2006.02.158

Abstract We report the first known case of septic arthritis in the setting of total hip arthroplasty caused by Clostridium cadaveris , a gas-forming anaerobic enteric organism usually considered a non-pathogen. This case occurred in a patient treated with total hip arthroplasty for metastatic breast cancer involving the acetabulum. The patient was managed successfully with debridement, prosthetic retention, and chronic antibiotic suppression. We propose this mode of care as a successful alternative for some patients with prosthetic joint infection and prohibitive comorbid conditions.