Efficient radical scavenging ability of artepillin C, a major component of Brazilian propolis, and the mechanism

Hydrogen transfer from artepillin C to cumylperoxyl radical proceeds via one-step hydrogen atom transfer rather than via electron transfer, the rate constant of which is comparable to that of (+)-catechin, indicating that artepillin C can act as an efficient antioxidant.

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Bibliographic Details
Published inOrganic & biomolecular chemistry Vol. 1; no. 9; pp. 1452 - 1454
Main Authors Nakanishi, Ikuo, Uto, Yoshihiro, Ohkubo, Kei, Miyazaki, Kentaro, Yakumaru, Haruko, Urano, Shiro, Okuda, Haruhiro, Ueda, Jun-Ichi, Ozawa, Toshihiko, Fukuhara, Kiyoshi, Fukuzumi, Shunichi, Nagasawa, Hideko, Hori, Hitoshi, Ikota, Nobuo
Format Journal Article
LanguageEnglish
Published England 07.05.2003
Subjects
Catechin - chemistry
Free Radical Scavengers - chemistry
Free Radical Scavengers - pharmacology
Free Radicals - antagonists & inhibitors
Free Radicals - chemistry
Hydrogen - chemistry
Kinetics
Nucleic Acid Synthesis Inhibitors
Peroxides - antagonists & inhibitors
Peroxides - chemistry
Phenylpropionates - chemistry
Phenylpropionates - pharmacology
Propolis - chemistry
Online AccessGet full text
ISSN1477-0520
1477-0539
DOI10.1039/b302098c

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Summary:Hydrogen transfer from artepillin C to cumylperoxyl radical proceeds via one-step hydrogen atom transfer rather than via electron transfer, the rate constant of which is comparable to that of (+)-catechin, indicating that artepillin C can act as an efficient antioxidant.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:1477-0520
1477-0539
DOI:10.1039/b302098c