Telomeres as hotspots for innate immunity and inflammation

• Published in: DNA repair Vol. 133; p. 103591
• Main Authors: Nassour, Joe, Przetocka, Sara, Karlseder, Jan
• Format: Journal Article
• Language: English
• Published: Netherlands 01.01.2024
• Subjects: Aging - genetics; Cellular Senescence; Humans; Immunity, Innate; Inflammation; Telomere; Aging; Telomeres; Innate immunity; Inflammation; Genome stability; Cancer

Aging is marked by the gradual accumulation of deleterious changes that disrupt organ function, creating an altered physiological state that is permissive for the onset of prevalent human diseases. While the exact mechanisms governing aging remain a subject of ongoing research, there are several cel...