Diagnosis and epidemiology of cirrhosis

Cirrhosis is defined histologically as an advanced form of progressive hepatic fibrosis with distortion of the hepatic architecture and regenerative nodule formation. It may be due to a variety of causes. It can be diagnosed incidentally on liver biopsy or hepatic imaging studies, or patients may pr...

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Bibliographic Details
Published inThe Medical clinics of North America Vol. 93; no. 4; p. 787
Main Authors Lefton, Harvey B, Rosa, Anthony, Cohen, Matthew
Format Journal Article
LanguageEnglish
Published United States 01.07.2009
Subjects
Alanine Transaminase - blood
Aspartate Aminotransferases - blood
Autoimmune Diseases - complications
Chronic Disease
Disease Progression
Hemochromatosis - complications
Hepatitis, Viral, Human - complications
Hepatolenticular Degeneration - complications
Humans
Liver - diagnostic imaging
Liver - pathology
Liver - physiopathology
Liver Cirrhosis - diagnosis
Liver Cirrhosis - epidemiology
Liver Cirrhosis - etiology
Liver Cirrhosis - pathology
Liver Cirrhosis - physiopathology
Liver Cirrhosis, Alcoholic - epidemiology
Liver Failure - mortality
Liver Function Tests
Obesity - epidemiology
Prognosis
Radiography
Risk Factors
Ultrasonography
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Summary:Cirrhosis is defined histologically as an advanced form of progressive hepatic fibrosis with distortion of the hepatic architecture and regenerative nodule formation. It may be due to a variety of causes. It can be diagnosed incidentally on liver biopsy or hepatic imaging studies, or patients may present clinically with one or more features of hepatic failure. This article gives the reader a broad overview of the epidemiology, diagnosis, and natural history of cirrhosis; laying the foundation for subsequent articles, which will discuss the diagnosis and management of each of the specific cirrhosis-related complications.
ISSN:1557-9859
DOI:10.1016/j.mcna.2009.03.002