Hiccups induced by aripiprazole combined with sertraline in an adolescent with olfactory reference disorder: A case report

Background: Hiccup can cause significant distress to patients and affect medication compliance. Individuals with olfactory reference disorder (ORD) who might develop persistent hiccups when treated with a combination of antidepressant and antipsychotic, leading to significant distress and impairment...

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Bibliographic Details
Published inFrontiers in psychiatry Vol. 13
Main Authors Li, Zhe, Xiong, Zhenzhen, Jiang, Xingmei, Li, Zhixiong, Yuan, Yiwen, Li, Xiao
Format Journal Article
LanguageEnglish
Published Frontiers Media S.A 25.07.2022
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Summary:Background: Hiccup can cause significant distress to patients and affect medication compliance. Individuals with olfactory reference disorder (ORD) who might develop persistent hiccups when treated with a combination of antidepressant and antipsychotic, leading to significant distress and impairment. Case summary We report a rare case of an adolescent with ORD who was treated with aripiprazole combined with sertraline and who began to hiccup persistently after 6 days on this treatment. He stopped hiccupping after the aripiprazole had been suspended for 12 h. After discharge, the patient continued on sertraline alone and reported no hiccupping at 1-month follow-up. Conclusion Clinicians should consider that the combination of aripiprazole and sertraline can induce hiccups during the acute administration period in adolescents with ORD.
Bibliography:This article was submitted to Child and Adolescent Psychiatry, a section of the journal Frontiers in Psychiatry
Reviewed by: Piotr Ratajczak, Poznan University of Medical Sciences, Poland; Srinivas Dannaram, Banner - University Medical Center Phoenix, United States
These authors have contributed equally to this work and share first authorship
Edited by: Paramala Janardhanan Santosh, King's College London, United Kingdom
ISSN:1664-0640
1664-0640
DOI:10.3389/fpsyt.2022.793716