Subependymal giant cell astrocytoma with intratumoral hemorrhage in the absence of tuberous sclerosis

• Published in: Journal of clinical neuroscience Vol. 15; no. 6; pp. 704 - 706
• Main Authors: Stavrinou, P, Spiliotopoulos, A, Patsalas, I, Balogiannis, I, Karkavelas, G, Polyzoidis, K, Selviaridis, P
• Format: Journal Article
• Language: English
• Published: Scotland Elsevier Ltd 01.06.2008
• Subjects: Adult; Astrocytoma - complications; Brain Neoplasms - complications; Glial Fibrillary Acidic Protein - metabolism; Hemorrhage - etiology; Humans; Intratumoral hemorrhage; Intraventricular hemorrhage; Magnetic Resonance Imaging; Male; Neurology; Subependymal giant cell astrocytoma; Tomography, X-Ray Computed - methods; Tuberous sclerosis; Tuberous sclerosis; Intraventricular hemorrhage; Intratumoral hemorrhage; Subependymal giant cell astrocytoma
• ISSN: 0967-5868; 1532-2653
• DOI: 10.1016/j.jocn.2007.06.003

Abstract Subependymal giant cell astrocytoma (SEGA) is an uncommon tumor that usually occurs in the setting of tuberous sclerosis (TS) syndrome. We report a rare case of an intratumoral and a small intraventricular hemorrhage complicating a SEGA in an adult patient without any signs of TS. Although pre-operative CT and MRI findings for the tumor were typical of SEGA, SEGA was not considered in the differential diagnosis because the patient was lacking any symptoms of TS. This is the second report of intraventricular and intratumoral hemorrhage complicating a SEGA and the first case in which these complications occurred in an adult patient in whom there was no previous suspicion of systemic disease.