Selected ion flow tube mass spectrometry of urine headspace

We describe the use of our selected ion flow tube mass spectrometric technique (SIFT‐MS) for the analysis of the headspace above urine. Ammonia, nitric oxide, acetone, ethanol and methanol are identified as the dominant species. As expected, the ammonia is increased in the headspace by making the ur...

Full description

Saved in:
Bibliographic Details
Published inRapid communications in mass spectrometry Vol. 13; no. 8; pp. 724 - 729
Main Authors Smith, David, Španěl, Patrik, Holland, Tracey A., Al Singari, Waleed, Elder, James B.
Format Journal Article
LanguageEnglish
Published Chichester, UK John Wiley & Sons, Ltd 01.01.1999
Subjects
Acetone - urine
Ammonia - urine
Ethanol - urine
Humans
Hydrogen-Ion Concentration
Mass Spectrometry
Methanol - urine
Nitric Oxide - chemistry
Oxygen - chemistry
Urinalysis - instrumentation
Online AccessGet full text

Cover

More Information
Summary:We describe the use of our selected ion flow tube mass spectrometric technique (SIFT‐MS) for the analysis of the headspace above urine. Ammonia, nitric oxide, acetone, ethanol and methanol are identified as the dominant species. As expected, the ammonia is increased in the headspace by making the urine alkaline and the nitric oxide is increased by making the urine acidic. Nitric oxide is abnormally high in the headspace of acidified bacterially infected urine and nitrous acid is also detected. The potential clinical implications of analyses of urine by SIFT‐MS are alluded to. Copyright © 1999 John Wiley & Sons, Ltd.
Bibliography:Grant Agency of the Czech Republic - No. 203/97/P130
ark:/67375/WNG-R2JRRH2P-B
North Staffordshire Medical Institute, UK
ArticleID:RCM548
istex:6A848D69C35DC371FE944F2B526F24818B3522C4
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0951-4198
1097-0231
DOI:10.1002/(SICI)1097-0231(19990430)13:8<724::AID-RCM548>3.0.CO;2-E