The effectiveness of antihistamines in the common cold

A randomized, double-blind, placebo-controlled study was done on 106 volunteers to assess the effectiveness of chlorpheniramine maleate against the common cold. The results suggest that this antihistamine is significantly effective in relieving the symptoms of a cold if used four times daily for one...

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Bibliographic Details
Published inJournal of clinical pharmacology Vol. 21; no. 1; p. 9
Main Authors Crutcher, J E, Kantner, T R
Format Journal Article
LanguageEnglish
Published England 01.01.1981
Subjects
Adult
Chlorpheniramine - administration & dosage
Chlorpheniramine - adverse effects
Chlorpheniramine - analogs & derivatives
Chlorpheniramine - therapeutic use
Clinical Trials as Topic
Common Cold - complications
Common Cold - drug therapy
Double-Blind Method
Female
Humans
Male
Sleep Stages - drug effects
Smoking
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Summary:A randomized, double-blind, placebo-controlled study was done on 106 volunteers to assess the effectiveness of chlorpheniramine maleate against the common cold. The results suggest that this antihistamine is significantly effective in relieving the symptoms of a cold if used four times daily for one week, and that relief was gained with no significant increase in side effects.
ISSN:0091-2700
DOI:10.1002/j.1552-4604.1981.tb01725.x