The relationship between age of onset and risk factors including family history and life style in Korean population with type 2 diabetes mellitus

• Published in: Journal of Physical Therapy Science Vol. 30; no. 2; pp. 201 - 206
• Main Authors: Noh, Jin-Won, Jung, Jin Hee, Park, Jeong Eun, Lee, Jung Hwa, Sim, Kang Hee, Park, Jumin, Kim, Min Hee, Yoo, Ki-Bong
• Format: Journal Article
• Language: English
• Published: Japan The Society of Physical Therapy Science 01.01.2018; Japan Science and Technology Agency
• Subjects: Age; Age of onset; Diabetes; Family history; Lifestyles; Original; Population; Risk factors; Type 2 diabetes mellitus; Age of onset; Family history; Type 2 diabetes mellitus
• ISSN: 0915-5287; 2187-5626
• DOI: 10.1589/jpts.30.201

[Purpose] The purpose of the present study was to assess the relationship between age of onset and risk factors including family history and life style in Korean population with type 2 diabetes mellitus (T2D). [Subjects and Methods] Subjects with T2D patients who received outpatient care for blood sugar control were randomly sampled at 13 general hospitals and 969 subjects were included. Cox proportional hazard models were used to confirm associations between age of onset and risk factors including family history and life style in Korean population with T2D. [Results] Parent history of T2D was significantly associated with age of onset. Compared to none of family members with T2D, those whose both father and mother had a history showed the highest the risk of early-onset (HR=2.36; 95% CI=1.45–3.85). Mother and father’s history of T2D (HR=1.73; 95% CI=1.46–2.05; HR=1.83; 95% CI=1.40–2.37) were associated with the risk of early-onset. Moreover, exercise (HR=1.23, CI=1.08–1.40) smoking status (HR=1.62, CI=1.32–1.99), and drinking (HR=1.32, CI=1.13–1.54) were associated with a higher risk for the early-onset. [Conclusion] Family history as well as life style including exercise, smoking, and drinking are the risk factors for early-onset factor in Korean population with T2D.