Implantable optical-electrode device for stimulation of spinal motoneurons

Recent years, optogenetic method of scientific research has proved its effectiveness in the nerve cell stimulation tasks. In our article we demonstrate an implanted device for the spinal optogenetic motoneurons activation. This work is carried out in the Laboratory of Molecular Neurodegeneration of...

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Bibliographic Details
Published inJournal of physics. Conference series Vol. 741; no. 1; pp. 12071 - 12077
Main Authors Matveev, M V, Erofeev, A I, Zakharova, O A, Pyatyshev, E N, Kazakin, A N, Vlasova, O L
Format Journal Article
LanguageEnglish
Published Bristol IOP Publishing 01.08.2016
Subjects
Fiber optics
Genetic modification
Laboratories
Microelectrodes
Optical waveguides
Physics
Stimulation
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Summary:Recent years, optogenetic method of scientific research has proved its effectiveness in the nerve cell stimulation tasks. In our article we demonstrate an implanted device for the spinal optogenetic motoneurons activation. This work is carried out in the Laboratory of Molecular Neurodegeneration of the Peter the Great St. Petersburg Polytechnic University, together with Nano and Microsystem Technology Laboratory. The work of the developed device is based on the principle of combining fiber optic light stimulation of genetically modified cells with the microelectrode multichannel recording of neurons biopotentials. The paper presents a part of the electrode implant manufacturing technique, combined with the optical waveguide of ThorLabs (USA).
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/741/1/012071