Facial Transplantation

Reconstruction of severe facial deformities poses a unique surgical challenge: restoring the aesthetic form and function of the face. Facial transplantation has emerged over the last decade as an option for reconstruction of these defects in carefully selected patients. As the world experience with...

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Bibliographic Details
Published inFacial plastic surgery clinics of North America Vol. 24; no. 3; p. 367
Main Authors Russo, Jack E, Genden, Eric M
Format Journal Article
LanguageEnglish
Published United States 01.08.2016
Subjects
Drug Therapy, Combination
Facial Transplantation - ethics
Facial Transplantation - methods
Facial Transplantation - psychology
Graft Rejection - immunology
Graft Rejection - prevention & control
Humans
Immunosuppressive Agents - therapeutic use
Patient Selection
Treatment Outcome
Ethics
Immunosuppression
Microvascular surgery
Composite tissue allotransplantation
Facial transplantation
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Summary:Reconstruction of severe facial deformities poses a unique surgical challenge: restoring the aesthetic form and function of the face. Facial transplantation has emerged over the last decade as an option for reconstruction of these defects in carefully selected patients. As the world experience with facial transplantation grows, debate remains regarding whether such a highly technical, resource-intensive procedure is warranted, all to improve quality of life but not necessarily prolong it. This article reviews the current state of facial transplantation with focus on the current controversies and challenges, with particular attention to issues of technique, immunology, and ethics.
ISSN:1558-1926
DOI:10.1016/j.fsc.2016.03.013